The AIDS Linked to the Intravenous Experience (ALIVE) Study is a long-standing community based research effort that includes past and current injection drug users (IDUs).
Notable findings from ALIVE include:
- Temporal trends in substance use
- Occurrence of age-associated NCDs among HIV-infected PWID
- Barriers to HIV care engagement
Between 2015 and 2017, ALIVE complete a new recruitment of 600 PWID. ALIVE is also adding a mobile recruitment and follow-up facility and linking with the Marland Health Information Exchange for Medical Outcome Data.
New survey instruments that have been implemented or are planned include:
- Enhanced geospatial data on locations of drug use/service utilization
- Adverse childhood experience
- Patient activation
- Pain severity
- Perceptions related to chronic disease management
ALIVE plans to continue looking at temporal trends in the opioid epidemic, including characterization of shifting drug profiles and context over time and their impact on the incidence of fatal and non-fatal overdose, HIV and HCV infection and mortality. The cohort also plans to examine the dynamic associations between HIV care continuum outcomes and prevalence and control of non-communicable diseases (NCDs), and their joint impact on morbidity, mortality, and quality of life.