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The Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) is the coordinating center for the National Institute on Drug Abuse (NIDA) U01 cohorts. C3PNO manages and stimulates the use of the NIDA longitudinal cohorts and addresses high priority research on HIV/AIDS in the context of substance misuse.

C3PNO is focused on cutting-edge science powered by the cohorts' combined sample size of approximately 12,000 participants. We have assembled a team of researchers with global leadership in HIV prevention, clinical science and co-morbidities, behavioral science, immunology, modeling, and bioethics to work with NIDA program scientists to align and stimulate the highest impact science across NIDA-funded cohorts that have compiled unique repositories of varied and rich data.

History

The National Institute of Drug Abuse (NIDA) has created a unique group of cohorts to study how HIV affects and is affected by substance use.

These cohorts have been productive in creating high-impact science, particularly related to the role of injection drug use on the HIV epidemic and the importance of co-morbidities such as Hepatitis C (HCV) and cardiovascular disease. The oldest cohort (ALIVE) was created near the discovery of HIV/AIDS. NIDA has continued to issue awards in response to the changing nature of the epidemic in North America.

C3PNO

The Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) is managed by UCLA and Frontier Science. The project has assembled a team of researchers with global leadership in HIV prevention, clinical science and co-morbidities, behavioral science, immunology, modeling, and bioethics. C3PNO works with NIDA program scientists to align and stimulate the highest impact science across NIDA-funded cohorts.

Staff and Organizations

C3PNO is a collaboration between the 9 NIDA U01 cohorts, The University of California, Los Angeles (UCLA), and Frontier Science.