The Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) project is a consortium of nine cohorts studying the intersection of HIV infection and substance abuse.

COVID-19: C3PNO Cohort PIs

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What is C3PNO?

The Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) is the coordinating center for the National Institute on Drug Abuse (NIDA) U01 cohorts. C3PNO manages and stimulates the use of the NIDA longitudinal cohorts and addresses high priority research on HIV/AIDS in the context of substance misuse.

C3PNO is focused on cutting-edge science powered by the cohorts’ combined sample size of approximately 12,000 participants. We have assembled a team of researchers with global leadership in HIV prevention, clinical science and co-morbidities, behavioral science, immunology, modeling, and bioethics to work with NIDA program scientists to align and stimulate the highest impact science across NIDA-funded cohorts that have compiled unique repositories of varied and rich data.

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Submit a Concept to Request C3PNO Data

Researchers may request to use data collected by the C3PNO cohorts. You can search for available data on the Virtual Data Repository and then submit a concept to formally request data and specimens.

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Recent News

New Funding Opportunity: High Priority HIV and Substance Use Research

The National Institute of Health (NIH) has announced a new funding opportunity, "High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)" (RFA-DA-22-040). The purpose of this initiative is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use.

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National Ending the HIV Epidemic (EHE) 2021 Meeting

On April 14-15, 2021, more than 300 academic investigators, government scientists, local health department professionals, and community members from throughout the U.S. participated in the virtual National Ending the HIV Epidemic (EHE) Meeting hosted by the National Institutes of Health (NIH) and the DC Center for AIDS Research (CFAR).

The meeting featured presentations by academic investigators and their implementation and community partners funded through NIH EHE awards and highlighted their data and experiences to date. In addition, Implementation Science Coordination, Consultation, & Collaboration Initiative (ISC3I) hosted a series of methods workshops for HIV implementation research and practice for the 2020 EHE project teams.

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